CytoSolve - In-Silico drug development, From molecules to market
CytoSolve - A new paradigm in drug development

Providing technology and services towards accelerating drug development using an integrative platform for quantitative modeling of complex molecular pathways. Using in-silico modeling to bridge in-vitro testing to human clinical trials with the goal of eliminating animal experimentation.

In-Silico Model Integration

A new system for integrating an ensemble of distributed biochemical network models is presented. Rapid growth in the number of biochemical network models, created in different formats, across different computing systems, with minimal input and output information, necessitates the need for such a system in order to build large scale models in a flexible and scalable manner.

From Molecules to Market

Biomolecular pathways are building blocks of cellular biochemical function. Computational biology is in rapid transition from diagrammatic representation of pathways to quantitative and predictive mathematical models, which span time-scales, knowledge domains and spatial-scales. This transition is being accelerated by high-throughput experimentation which isolates reactions and their corresponding rate constants.

Papers

OREMPdb: A Semantic Dictionary Of Computational Pathway
CytoSolve: A Scalable Computational Method for Dynamic Integration of Multiple Molecular Pathway Models
A Distributed Computational Architecture for Integrating Multiple Biomolecular Pathways
Integrating an Ensemble of Distributed Biochemical Network Models
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